Research Associate - Biology

Amicus Therapeutics is a clinical stage biopharmaceutical company dedicated to the development of small-molecule, orally-active drugs for the treatment of a broad range of human genetic diseases. The company is rapidly developing its proprietary platform technology into a robust clinical and pre-clinical pipeline. This unique technology represents a paradigm-shifting, next generation approach to the management of genetic diseases which offers the potential to dramatically improve treatment options for patients.


Amicus' technology utilizes pharmacological agents to combine selectively with the diseased protein target and reverse or reduce the effects of the gene mutation. Pharmacologic chaperones offer several advantages over competing approaches to treat genetic disorders including oral delivery and the ability to treat difficult to reach tissues. Amicus' lead drug candidates are for lysosomal storage diseases, a severe class of genetic diseases characterized by serious and often life-threatening illness.


Amicus is funded by some of the most preeminent venture capital firms in health care, including NEA, Prospect Ventures, Frazier Health Care Ventures, CHL Medical and Canaan Partners. The company has built a first rate senior management team with a significant track record of success in this industry.


The company is headquartered in Cranbury, NJ. Amicus has a fast-paced, high-energy, entrepreneurial team environment where employees are encouraged to be innovative and resourceful. Amicus seeks high-caliber, talented individuals with a passion to succeed. Additional information on the company, product pipeline, and technology is available at www.amicustherapeutics.com.
Responsibilities:

Our state-of-the art laboratory uses a combination of cell-biology, genetic, and biochemical approaches to study neurodegenerative diseases caused by defects in protein folding. In this position, the Research Associate will have responsibilities including but not limited to: mammalian cell culture; cell transfection, maintenance of cell lines, cell-based experiments; plate-based assays; plasmid construction and amplification; protein purification & biochemical characterization; write reports and prepare slide presentations.
REQUIREMENTS


Requirements/Qualifications:



A BS in biology and 3+ years of laboratory experience, or MS with 1+ year of laboratory experience is required. The successful candidate will have proven cell and molecular biology skills, including experience with culturing and transfecting mammalian cells, designing and constructing plasmids, PCR, qRT-PCR, fluorescent plate-based assays, and basic protein purification and characterization by SDS-PAGE. Strong interpersonal, oral and written communication skills are imperative. The candidate will have exceptional record-keeping skills and show attention to detail when conducting experiments. Exhibiting a sense of urgency and the ability to work under tight deadlines is a must. The candidates must be able to demonstrate initiative, innovative thinking, and the ability to work collaboratively with other scientists in a fast-paced and rapidly-changing team environment.

Amicus Therapeutics offers a competitive compensation and benefits package including, medical, dental, disability, life insurance, flexible spending accounts, 401k and stock options.


Qualified candidates please submit your résumé to:
Email: [Click here for email]
fax: 609-662-2001

Amicus Therapeutics is an equal opportunity employer.

NO PHONE CALLS PLEASE




Job Code CB-MB-RA-0609